Saturday, December 4, 2021

Revista Gastroenterología

December 2021

Bowel

Endoscopic submucosal dissection (ESD) in Germany:

ESD achieved excellent en bloc resection rates but only modest curative resection rates in a German prospective ESD registry comprising 1000 lesions. Moreover, the results varied significantly depending on the center’s yearly case volume.

Ozanimod for ulcerative colitis:

The sphingosine-1-phosphate receptor modulator Ozanimod was more effective than placebo as induction and maintenance therapy in patients with moderately to severely active ulcerative colitis.

Liver

Steroids in alcohol-associated hepatitis (CONTRA):

A current observational study shows that both, patients with severe alcohol-associated hepatitis as well as patients with decompensated alcohol-associated cirrhosis are very susceptible to infection. Patients with severe alcohol-associated hepatitis or a high MELD score (model for end-stage liver disease) have a particularly high risk. However, the main risk factor for invasive fungal infection is steroid treatment, not severe alcohol-associated

Steroids in alcohol-associated hepatitis (PRO):

A recent retrospective, international, multicenter cohort study shows that steroids improve 30-day survival in patients with severe alcohol-associated hepatitis, especially those with a MELD score (model for end-stage liver disease) between 25 and 39.

Non-alcoholic fatty liver disease (NAFLD):

A current prospective study demonstrates the important impact of fibrosis stage on prognosis of NAFLD: Fibrosis stages F3 and F4 are associated with increased risks of liver-related complications (variceal hemorrhage, ascites, encephalopathy, or hepatocellular carcinoma) and death.

Oesophagus Stomach Duodenum

Pancreas

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