Revista Gastroenterología

March 2021

Bowel

Motorized spiral endoscopy

This first prospective clinical feasibility study comprising 140 interventions demonstrated that motorized spiral endoscopy has a high diagnostic yield of 74,2% with an acceptable spectrum of side effects.

Fecal microbiota transfer (FMT) for patients with irritable bowel syndrome (IBS):

In a randomized trial of patients with refractory IBS with predominant bloating, FMT relieved symptoms compared to placebo (transfer of autologous stool). The effects decreased after 1 year and could be restored by a second FMT in patients with prior response. Clinical response was also associated with composition of the fecal microbiota which may serve as biomarker for future response to therapy.

Liver

Postoperative mortality in cirrhosis

A new online tool substantially improves postoperative mortality predictions in patients with cirrhosis. Predictors include age, preoperative albumin, platelet count, bilirubin, surgery category, emergency indication, fatty liver disease, ASA (American Society of Anesthesiologists) classification, and obesity. (www.vocalpennscore.com)

Autoimmune hepatitis (AIH)

The simplified criteria for the diagnosis of AIH include immunofluorescence testing of antinuclear and smooth muscle autoantibodies (ANA and SMA) on rodent tissue sections. A current study demonstrates that at adjusted cut-offs, both ANA immunofluorescence testing using human epithelioma-2 cells and ELISA-based autoantibody evaluation for ANA and SMA are potential alternatives.

Oesophagus Stomach Duodenum

Helicobacter pylori eradication for prevention of gastric cancer

Population-based eradication of H. pylori significantly reduced gastric cancer incidence in a high-risk cohort in Taiwan without causing significant side effects. However, there was no impact on tumor-associated mortality, but the follow-up may not have been sufficiently long to address this question.

Pancreas

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